NinePoint Medical 

12 Oak Park Drive

Bedford, MA 01730

Phone: (617) 250-7190
Fax: (617) 250-7199

  • Twitter
  • LinkedIn
  • YouTube

© 2019 NinePoint Medical, Inc. NvisionVLE® and NinePoint Medical are registered trademarks of NinePoint Medical, Inc. NinePoint Medical was founded in partnership with Third Rock Ventures and Prospect Ventures. (900064 Rev. F)


At the heart of the NvisionVLE® Imaging System is our state-of-the-art Optical Coherence Tomography (OCT) imaging hardware, providing physicians with comprehensive volumetric images of the esophagus and bile duct in real-time.

OCT transmits infrared (invisible) light into tissue, and measures back-reflected light from the tissue microstructure to see beneath the surface.  While similar in concept to ultrasound, OCT uses light instead of ultrasonic waves to produce higher-resolution images.

  • Subsurface: Image up to 3 mm beneath the tissue surface

  • Volumetric: Image 100% of the tissue over a 6 cm scan length

  • High Resolution: 7 microns

  • Real-time: User-controlled imaging

  • Fast: Complete automated volumetric scans in as little as 20 seconds

This creates a Volumetric Laser Endomicroscopy (VLE) procedure that is...


See what other technologies can't. 

See beneath the surface, up to 3 mm deep, unlike white light endoscopy which can only image surface detail​


See the full picture, 100% of the tissue in a 6 cm volumetric scan, as opposed to a “point” image obtained with confocal microscopy (CLE)


See in high resolution, 7 microns, up to 25X higher resolution than endoscopic ultrasound

Focus on what matters, use artificial intelligence (AI) algorithms for real-time detection and colorization of esophageal image features to aid image review

Target with confidence, create real-time superficial laser marks to guide tissue acquisition in areas of interest that may not be visible with other technologies


A Closer Look


State-of-the-art console designed for clinicians, with flexibility and functionality in mind

  • Rapid Setup, easy mobility, and user-friendly controls

  • High resolution touch screens for simple and elegant interrogation of data

User Interface

Intuitive display of three-dimensional volumetric scan data

Cross-sectional view: See beneath the surface

  • 7 micron resolution

  • 3 mm deep

  • 1200 cross-sectional scans over a 6 cm scan length

ROI view: See up close, within a region of interest

Longitudinal view: See along the axis of the organ

  • 4000 images over 360 degrees

En face view: See an overview of the entire scan in one two-dimensional image 

High-Speed Optical Probe

Advanced miniaturized optics rotate and retract at high speeds to provide real-time subsurface volumetric images

  • Balloon catheter facilitates positioning and centering in the esophagus, available in 14 mm, 17 mm, and 20 mm diameter

  • Balloon-less Low-Profile Optical Probe accommodates the narrow anatomy of the pancreatico-biliary system

  • Compatible with endoscope working channels 2.8 mm and larger

Hand Controller

Intuitive hand controller gives complete real-time physician control of the exam

  • Attach to endoscope and control the VLE procedure while at the patient bedside

  • Complete workflow control at your fingertips



At NinePoint Medical, we push the limits of engineering and innovation to provide value to gastroenterologists and their patients.

2013: NvisionVLE® Imaging

System Launch

  • First FDA-cleared OCT imaging system for gastroenterology applications

  • Helping gastroenterologists care for their patients; seeing abnormalities beneath the tissue surface where other technologies can't

  • Press Release

2016: Real-time Targeting™

(RTT) Launch

  • Only feature of its kind in the market

  • Creates real-time superficial laser marks to guide tissue acquisition at esophageal areas of interest that may not be visible with other technologies

  • Press Release

2018: Intelligent Real-time Image Segmentation™ (IRIS)

  • First FDA-cleared artificial intelligence imaging product for gastroenterology

  • Real-time detection and colorization of esophageal image features to aid image review

  • Press Release

Learn More

Learn More About Biliary Applications

Looking for More?  Contact Us